block the joints to reduce inflammation, this is possible in some cases

What are the limitations of this injection treatment to fight osteoarthritis?

The only cases affected are osteoarthritis of the knee where medical treatment has failed. The results are confirmed by other trials, especially in Japan, but with small numbers and different products injected. Hence the interest of the new ongoing study carried out with the Clinical Research Program of the Hospital (PHRC) with 130 patients who are not candidates for surgery. Two thirds are treated with lipiodol, based on a natural plant extract, with one third receiving a placebo*. The expected conclusion in two to three years.

* For this study, 130 patients with osteoarthritis of the knee, who have failed medical treatment and are not candidates for surgery, will be recruited. Registration possible at

• Treatment of osteoarthritis of the knee with this treatment, when will it be possible?

This technique is already used by interventional radiologists in Nîmes, Montpellier, Grenoble, Paris (Hospital Europe Georges-Pompidou), Lyon, Bordeaux, but to date only for compassionate purposes, that is after failure of all other treatments. The new study aims to expand eligible patients.

No experts

Pre Christelle Nguyen from the department of physical medicine and rehabilitation of the Cochin hospital in Paris.

Professor Marc Sapoval head of the interventional radiology department at the European Georges-Pompidou Hospital in Paris.

Professor Francis Berenbaum head of the rheumatology department at the Saint-Antoine hospital and head of the Inserm team “Joint pathology associated with metabolic diseases and age” in Paris.

Professor Yves-Marie Persrheumatologist at the University Hospital of Montpellier.

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